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Immunogenetics and Transplantation Lab

Lee Ann Baxter-Lowe, PhD

Professor of Surgery in Residence

Director, Immunogenetics & Transplantation Laboratory

Support the Lab

Your generous support of the Immunogenetics and Transplantation Laboratory helps scientists discover new treatments for bone marrow, cornea transplantation and more.

Diagnostic Testing, Research & Education

The Immunogenetics and Transplantation Laboratory (ITL) provides specialized diagnostic services for allogeneic transplantation and conducts related research. The laboratory provides support for blood, bone marrow, kidney, pancreas, liver, heart, lung, small bowel, and cornea transplantation. The Immunogenetics and Transplantation Laboratory is a national reference laboratory, a referee laboratory for the ASHI proficiency testing program, a NMDP contract laboratory, a core laboratory for the NIH Immune Tolerance Network, and a participant in several national clinical trials. The laboratory also conducts basic research and provides educational programs for health care professionals. The laboratory is not-for-profit and is owned and operated by the University of California, San Francisco.

Recent Publications

Baxter-Lowe LA, Maiers M, Spellman SR, Haagenson MD, Wang T, Fernandez-Vina M, Marsh SG, Horowitz M, Hurley CK
HLA-A disparities illustrate challenges for ranking the impact of HLA mismatches on bone marrow transplant outcomes in the United States.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, Aug-01-2009; 158: 971-81.
Waxman IM, Militano O, Baldinger L, Roman E, Qualter E, Morris E, Garvin J, Bradley MB, Bhatia M, Satwani P, George D, Del Toro G, Hawks R, Wolownik K, Foley S, Cheung YK, Schwartz J, van de Ven C, Baxter-Lowe LA, Cairo MS
Sequential administration of sargramostim and filgrastim in pediatric allogeneic stem cell transplantation recipients undergoing myeloablative conditioning.
Pediatric transplantation, Jun-01-2009; 134: 464-74.  Epub 2008 Sep 10.
Dvorak CC, Gilman AL, Horn B, Jaroscak J, Dunn EA, Baxter-Lowe LA, Cowan MJ
Clinical and immunologic outcomes following haplocompatible donor lymphocyte infusions.
Bone marrow transplantation, May-04-2009; [Epub ahead of print].
Horn B, Soni S, Khan S, Petrovic A, Breslin N, Cowan M, Pelle-Day G, Cooperstein E, Baxter-Lowe LA
Feasibility study of preemptive withdrawal of immunosuppression based on chimerism testing in children undergoing myeloablative allogeneic transplantation for hematologic malignancies.
Bone marrow transplantation, Mar-01-2009; 436: 469-76.  Epub 2008 Oct 27.
Shi J, Tricot G, Szmania S, Rosen N, Garg TK, Malaviarachchi PA, Moreno A, Dupont B, Hsu KC, Baxter-Lowe LA, Cottler-Fox M, Shaughnessy JD, Barlogie B, van Rhee F
Infusion of haplo-identical killer immunoglobulin-like receptor ligand mismatched NK cells for relapsed myeloma in the setting of autologous stem cell transplantation.
British journal of haematology, Dec-01-2008; 1435: 641-53.  Epub 2008 Oct 16.
Kurtzberg J, Prasad VK, Carter SL, Wagner JE, Baxter-Lowe LA, Wall D, Kapoor N, Guinan EC, Feig SA, Wagner EL, Kernan NA, Kernan NA
Results of the Cord Blood Transplantation Study (COBLT): clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with hematologic malignancies.
Blood, Nov-15-2008; 11210: 4318-27.  Epub 2008 Aug 21.
John J. Garcia, Lan T. Vu, Peter Stock, Lee Ann Baxter Lowe.
Efficacy of Labscreen Reagents for Detection of Post Transplant HLA Antibodies.
Human Immunology, Oct-16-2008; [In Press] 69Supplement 1: S36.
Lee Ann Baxter Lowe, Lan Vu, John Garcia, Peter Stock
The Impact of HLA Disparity in Pediatric Kidney Recipients.
Human Immunology, Oct-16-2008; [In Press] 69Supplement 1: S39 .
Ozyurek E, Cowan MJ, Koerper MA, Baxter-Lowe LA, Dvorak CC, Horn BN
Increasing mixed chimerism and the risk of graft loss in children undergoing allogeneic hematopoietic stem cell transplantation for non-malignant disorders.
Bone marrow transplantation, Jul-01-2008; 422: 83-91.  Epub 2008 Apr 07.
Williams TM, Winden T, Setterholm M, Vierra-Green CA, Spellman S, Flesch S, Awdeh Z, Baxter-Lowe LA, Begovich AB, Fernandez-Vina M, Hegland J, Hurley CK, Johnson D, Noreen H, Salazar M, Schmeckpeper B, Yunis EJ
Strategies and technical challenges in allele level Class II typing in 2578 bone marrow transplantation donor-recipient pairs.
Human immunology, 694-5: 227-34.  Epub 2008 Apr 25.
Lee SJ, Klein J, Haagenson M, Baxter-Lowe LA, Confer DL, Eapen M, Fernandez-Vina M, Flomenberg N, Horowitz M, Hurley CK, Noreen H, Oudshoorn M, Petersdorf E, Setterholm M, Spellman S, Weisdorf D, Williams TM, Anasetti C
High-resolution donor-recipient HLA matching contributes to the success of unrelated donor marrow transplantation.
Blood, Dec-15-2007; 11013: 4576-83.  Epub 2007 Sep 4.
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